There is either one universe or many universities. It's all a matter of perspective. Both are equally true.
But when you have one, many are impossible. If you have many, one is impossible. That's a common mistake causing profound confusion.
There cannot be separation and controlled variables in a universe.
There cannot be variation and interaction in many universities.
This is irrelevant from a pragmatic point of view, because there "relatively" true is good enough. To understand the universal fundamentals, it is the most important point of all points.